Publication

Long-Term Fatigue After Treatment for Breast Cancer

The UPBEAT cohort study examined persistent fatigue following breast cancer treatment and its relationships with psychological symptoms and cardiovascular function.

Avis NE, O’Connell NS, Mihalko SL, et al.
JAMA Network Open · 2026

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UPBEAT (Understanding and Predicting Breast Cancer Events After Treatment) follows women receiving breast cancer treatment alongside a comparison group without cancer. This analysis examined fatigue through two years after treatment began, including its associations with depressive symptoms, perceived stress, and measures of cardiac function.

Citation

Avis NE, O’Connell NS, Mihalko SL, et al. Long-Term Fatigue After Treatment for Breast Cancer. JAMA Network Open. 2026;9(8):e2629862. DOI.